Alex Pouget, Associate Professor of Brain and Cognitive Sciences

Researchers at the University of Rochester may have answered one of neuroscience’s most vexing questions—how can it be that our neurons, which are responsible for our crystal-clear thoughts, seem to fire in utterly random ways?

In the November issue of Nature Neuroscience, the Rochester study shows that the brain’s cortex uses seemingly chaotic, or “noisy,” signals to represent the ambiguities of the real world—and that this noise dramatically enhances the brain’s processing, enabling us to make decisions in an uncertain world.

“You’d think this is crazy because engineers are always fighting to reduce the noise in their circuits, and yet here’s the best computing machine in the universe—and it looks utterly random,” says Alex Pouget, associate professor of brain and cognitive sciences at the University of Rochester.

Pouget’s work for the first time connects two of the…