13 May 2026
Antibiotics are losing their effectiveness. With the growth of antimicrobial resistance, routine treatments could become impossible owing to the risk of infection. Cancer treatments, care of newborns and routine surgeries are all in danger if this trend isn’t curbed and millions of people are already dying from infections by antibiotic-resistant bacteria. This resistance rise won’t only cost lives. In 2023, the World Bank estimated that antimicrobial resistance could increase health-care costs by US$1 trillion by 2050. So, researchers are urgently looking for solutions.
Some of these might come from surprising places, and this has led researchers to investigate organisms at the planet’s extremes. Other scientists, however, have discovered a source of antibiotic-producing bacteria closer to home — at the grave of a faith healer.
While some researchers have turned to traditional folk stories for clues in the search for new medicines, others have been using artificial intelligence to speed up the discovery process for antibiotics, to help deliver drugs into bacteria and to help physicians decide when to prescribe antibiotics to help prevent their overuse.
Together, this research could unlock new antibiotics and find ways to make them last longer, avoiding a future in which bacterial infections make a resurgence.
00:00 The rise of antibiotic resistance
01:23 Investigating a grave for new antibiotics
04:13 Analyzing the grave soil in the lab
07:13 The need for new approaches
09:37 The promise of AI to find new antibiotics
10:32 Using AI to discover chemical tricks to get drugs into bacteria
14:13 How AI could be used to help prescribe antibiotics and prevent resistance
17:30 Researchers’ hopes for the future
Read more: https://www.nature.com/collections/hh…
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30 Apr 2026 The Rest Is Science
What can a humble airplane sick bag teach us about physics, engineering, and the limits of the human stomach; And why are there people out there collecting thousands of them?
Professor Hannah Fry and VSauce’s Michael Stevens turn an unlikely holiday prompt into a surprisingly rich exploration of flight. From the biology of motion sickness to the physics of turbulence, and from exploding crisp packets to next-generation aircraft design, they unpack how flying messes with your body and how science has made it (mostly) better.
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