26 Apr 2026 #Psychedelics #Neuroscience #Psilocybin
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In 1943, a Swiss chemist named Albert Hofmann accidentally discovered LSD – and with it, a class of molecules that would spend the next 80 years confusing, inspiring, and ultimately rewriting modern neuroscience.
This is the story of how psychedelics went from accidental discovery, to clinical breakthrough, to banned substance, to the most promising new class of drugs in psychiatry – and how, after decades of being misunderstood, we finally figured out what they’re actually doing in the brain.
⚠️ A note on safety
This video covers the history and neuroscience of psychedelic medicine, including ongoing clinical research. It is not a recommendation to use these substances. Outside of a regulated clinical setting, psychedelics carry real risks – particularly for people with a personal or family history of psychosis or bipolar disorder. If you’re struggling with mental health, please speak to your doctor.
#Psychedelics #Neuroscience #Psilocybin #LSD #MentalHealth #Serotonin
🧠 Chapters
00:00 – The discovery that changed neuroscience
01:24 – A colourful chapter in science
04:15 – The first LSD trials
05:53 – Treating alcoholism with acid
08:12 – MK Ultra and the CIA
10:38 – The serotonin connection
12:21 – How psychedelics work in the brain
16:22 – Inside the Imperial College brain scans
18:06 – Turning psychedelics into medicine
23:18 – Finally mastering the trip
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